出　典 Saito H, et al： Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation：results of a phase Ⅲ, randomized, double-blind clinical trial. J Thromb Haemost 5(1)：31-41, 2007 Aikawa N, et al： Thrombomodulin alfa in the treatment of infectious patients complicated by disseminated intravascular coagulation: subanalysis from the phase 3 trial. Shock 35(4)：349-354, 2011 ※図表に関しましては、割愛させていただいております。